Amakuru

Wigeze uhagarara ngo utekereze uburyo ibigo bikorerwamo ibya farumasi bishoboye kweza ibiyigize mubuvuzi bwawe neza? Igikoresho kimwe cyingenzi bashingiraho cyitwa Vacuum Rotating Evaporator. Iki gikoresho cyubwenge gifasha abakora imiti kuvanaho imiti no guhuriza hamwe ibintu neza kandi neza. Ariko ikora ite - kandi ni ukubera iki ari ngombwa cyane?

Iyi nzira iroroshye kuruta uko yumvikana - kandi igira uruhare runini mubikorwa bya farumasi bigezweho.

Uburyo Vacuum Ihinduranya Imashini ikora: Ubuyobozi bworoshye

Vacuum Rotating Evaporator, rimwe na rimwe byitwa impinduramatwara cyangwa “rotovap,” ni igikoresho gikoreshwa mu gukuramo buhoro buhoro amazi ava mu gisubizo. Irabikora mukugabanya umuvuduko uri mumashini, itera amazi guhinduka mubushyuhe buke. Muri icyo gihe, igisubizo kizunguruka muri flask, kigakora ubuso bunini bwo guhumeka no gufasha kwirinda ubushyuhe bwinshi.

Ubu buryo ni bwiza bwo gukoresha ibikoresho byangiza ubushyuhe-nkibisanzwe biboneka mu miti na laboratoire.

Uburyo Vacuum Ihinduranya Impumura Itezimbere Gukora Imiti

1. Kongera Ubuziranenge nubusobanuro

Muri farumasi, ubuziranenge nibintu byose. Vacuum Rotating Evaporator ifasha gukuramo ibishashara bidakenewe mubintu bikora, byemeza ko imiti iboneye yonyine ijya mumiti yanyuma. Kuberako inzira ikoresha ubushyuhe buke hamwe numuvuduko wa vacuum, harikibazo gito cyo kwangirika kwimiti.

2. Gutanga umusaruro mwiza, imyanda mike

Bitewe nuburyo bworoshye bwo guhumeka neza, ababikora barashobora kugarura imashanyarazi ihenze kugirango bongere gukoreshwa. Ibi ntibizigama amafaranga gusa ahubwo binashyigikira imikorere irambye. Raporo yakozwe na ScienceDirect ivuga ko kugarura imiti mu gukora imiti bishobora kugabanya ibiciro by’umusaruro kugera kuri 25%.

3. Umutekano Kubintu Byunvikana

Ibikoresho byinshi bya farumasi bimeneka iyo bishyushye. Imyuka ya vacuum izunguruka ifasha kwirinda iki kibazo muguhindura imyanda ahantu hatetse. Ibi bituma ibice byoroshye bitagira ingano, nibyingenzi kumiti igomba kuba nziza cyane.

Urugero rufatika: Uburyo Vacuum Ihinduranya Imyuka Ihindura uburyo bwa farumasi nyayo

Inzira nziza yo gusobanukirwa n'akamaro ka Vacuum Rotating Evaporator nukureba uburyo ikoreshwa muri laboratoire yimiti.

Kurugero, mu kigo cya farumasi giciriritse cyibanze ku musaruro wibikoresho bya farumasi (API), uva muburyo bwa gakondo bwo guhumeka ukajya muri 20L vacuum izenguruka ibyuka byateye imbere cyane. Laboratwari yatangaje ko kwiyongera kwa 30% by’ibipimo byo gukira no kugabanuka kw’ubushyuhe bugabanuka hejuru ya 40 ° C, ibyo bikaba byarafashaga kurinda ibintu byoroshye kwangirika kw’ubushyuhe.

Iterambere ntabwo ryazigamye ibiciro gusa - ryanatezimbere ubuziranenge bwibicuruzwa kandi ryemeza ko hubahirizwa amahame akomeye. Ibikoresho byoroheje, bigenzurwa no guhumeka byatumaga ikigo cyuzuza urwego rwo hejuru mugihe hagabanijwe gukoresha ingufu.

Uru rugero nyarwo rwerekana neza uburyo imyuka ihinduranya imyuka idakora neza gusa ahubwo ni ngombwa mubidukikije bikora imiti.

Ibintu byingenzi biranga gushakisha muri Vacuum izunguruka

Niba ufite uruhare mu gukora imiti, dore bimwe bigomba kuba bifite ibikoresho mubikoresho byawe:

1. Amashanyarazi manini (5L - 50L) yo kongera umusaruro

2. Guhindura Igenzura rya Vacuum Kugenzura neza

3. Ubushyuhe bwa Digital hamwe no guhinduranya kugirango ubone ukuri

4. Ibirahure biramba, birinda ruswa

5. Sisitemu yoroshye yo kuyisukura no kuyitaho

Guhitamo Umufatanyabikorwa Ukwiye Kumashanyarazi

Mugihe uhitamo icyuka kizunguruka kugirango gikoreshe imiti cyangwa imiti, ubuziranenge, burambye, nibikorwa bya tekiniki. Aho niho Sanjing Chemglass igaragara.

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5. Gushyira mu bikorwa byinshi: Byuzuye muburyo bwo gutunganya ibishashara, uburyo bwo kubikuramo, hamwe nakazi ko kweza muri laboratoire yimiti, imiti, n’ibinyabuzima.

Hamwe nuburambe bwimyaka mubikoresho byibirahure bya shimi, Sanjing Chemglass ntago itanga gusa - turi umufatanyabikorwa wawe wizewe mukubaka laboratoire yizewe twifashishije sisitemu ya vacuum igezweho.

Mugihe uruganda rukora imiti rugenda rutera imbere, ibikoresho nkaUmuyoboro wa Vacuumigira uruhare runini mu kubungabunga umutekano, ubuziranenge, no gukora neza. Waba urimo usubizaho ibishishwa, kweza ibimera, cyangwa kongera umusaruro, kugira moteri ikwiye bigira icyo bihindura.